Outstanding Researcher

Filippo Milano, M.D, Ph.D.

Associate Professor
Translational Science and Therapeutics Division, Fred Hutch

Director, Cord Blood Transplant Program
Fred Hutch

As the Director of the Cord Blood Transplant Program at the Fred Hutch Cancer Center, Dr. Filippo Milano is a physician-scientist whose research is focused on the use of umbilical cord blood as a source of stem cells for transplantation to treat blood cancers. He concentrates on clinical practice improvements with a goal of increasing the number of patients eligible for transplantation and to improve clinical outcomes for those who receive cord blood transplants. He has carried out pivotal analyses of blood cancer patients who have received transplants, comparing outcomes of cord blood recipients with those who had blood stem cell transplants from unrelated donors. Dr. Milano also studies the use of an experimental, off-the-shelf cord blood product designed to extend immunological protection to recipients of cord blood transplants until their donated cells are fully engrafted and proliferating.

Selection of Dr. Milano's research:

• Impact of Non HLA-matched off-the-shelf ex-vivo expanded cord blood progenitors on outcomes in patients undergoing cord blood transplantation
• Use of Non HLA-matched off-the-shelf ex-vivo expanded cord blood progenitors for patients with HIV undergoing cord blood transplantation
• Evaluation of the use of Treosulfan as part of the conditioning regimen in patients undergoing cord blood transplantation and haploidentical transplant
• Use of TCR gene therapy to cure viral infections in patients undergoing cord blood transplantation
• Use of a new molecule (UM171) to expand cord blood progenitors

CLICK HERE to learn about other STEM careers in the cord blood industry.